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1. Review: Mrs. Hanes, has been on Metformin for a month, she has come in for a check-up. The paperwork says she took her dose for today, but you overhear the receptionist tell the doctor that Mrs. Hanes ate a small pack of sandwich cookies 15 minutes ago in the waiting room. Explain what will happen to Mrs. Hanes blood sugar. Describe the process that the cookie will take from digestion to insulin release and excess glucose storage, first WITHOUT Metformin, and then explain where Metformin will have an impact. (6points)

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2. Based on the article from the link below answer the following question in your own words (4 points)

https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-014-0085-1

a. Give two possible mechanisms of action of metformin in inhibiting cancer

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